ON THE RIBOFLAVIN METABOLISM IN DIABETIC PATIENT

Abstract

The amount of riboflavin excreted in three hour urine at rest in diabetic patients was much more than that of normal subjects, and it tended to decrease with the fall of blood sugar level by medical treatment. The urinary excretion of riboflavin increased by the administration of glucose, ATP or glucose with ATP both in normal and diabetic subjects. By the intravenous injection of insuline, it was observed a fall of riboflavin level in blood, an increase of urinary excretion of riboflavin and a rise of riboflavin concentration of urine.