Abstract
In order to clarify whether thiamine applied topically in an ointment was absorbed from the skin or not, the thiamine absorption picture on the skin of rats and mice was observed histochemically with Araki and Chen's method. From histochemical findings, it was proved that the thiamine was remarkably absorbed from the skin when it was disolved in plastibase hydrophilic and chiefly absorbed from the sebaceous glandula and the epithelium of sulcus cutis.