Abstract
In order to prove the occurrence of β-hyrdoxyglutamic acid decarboxylase in brain, volumes of CO_2 released from β-hydroxyglutamic acid in the presence of a brain homogenate and pyriodoxal phosphate were measured, and γ-amino-β-hydroxybutyric acid was detected in the reaction mixture. The optimum pH, distribution and stability of the enzyme were investigated and compared with those of brain glutamic acid decarboxylase.
