Abstract
Colorimetric determination of homopantothenic acid, D(+)-N-(α, γ-dihydroxy-β, β-dimethylbutyryl)-γ-amino-butyric acid was described. Homopantothenic acid is hydrolyzed to γ-aminobutyric acid (GABA) in alkaline solution and its amino-nitrogen is determined colorimetrically at 465mμ with sodium 1,2-naphthoquinone-4-sulfonate at pH 8.8〜9.6. If GABA, one of decomposition products is contaminated, it can be eliminated by Amberlite CG-120 and then the above procedures can be applied.
