Abstract
The oxidation of 3-hydroxybutyrate by liver mitochondria of normal guinea pigs and of choline deficient ones were compared. The enzymic activities of intact and sonic disrupted mitochondria of choline deficient animals were found to be as less as 74 percent of those of normal animals. The cause of these low activities was not considered to depend upon NAD level of mitochondria. The differences of P : acetoacetate ratio and P : O ratio were not significant.
