Abstract
Thiamine deficient status was estimated by determining the transketolase activity in redcell hemolysate in normal children and in several sick status in childhood. Transketolase activity was expressed by TDP-effect which is the per cent increase of hexose after the addition of thiamine diphosphate into the hemolysate. The mean value of TDP-effect was 3.8 ± 1.1% in normal infants of artificial feeding, 8.8 ± 0.7% in early childhood, and 12.6 ± 0.7% in prepubescence, and their daily thiamine intakes were 0.78. 0.42 and 0.99 mg, respectively. There was slight thiamine deficiency in prepubescent stage. In orthostatic dysregulation and acetonemic vomiting, the activity was depressed. In bronchial asthma, recurrent abdominal pain, noctural enuresis, diarrhae and convulsion, there were no significant differences from the normal group. During hypothermic operation of children with heart diseases, the enzyme activity was not changed significantly in contrast to the preoperative stage.
