Abstract
When riboflavin 2', 3', 4', 5'-tetranicotinate (B_2-Nic) was added to rat liver homogenate previously irradiated with ultraviolet light, thiobarbituric acid value of the homogenate was decreased. This decrease depended on the concentration of B_2-Nic added and accompanied with the decrease in the amount of B_2-Nic. The presently observed effect of B_2-Nic was found to be ascribable to riboflavin part of B_2-Nic. Accordingly, it is considered that riboflavin part of B_2-Nic reacts with lipoperoxide, resulting in the mutual decomposition.