Relative Activity of Niacin Related Compounds to Nicotinic Acid as Niacin Nutriture in Lactobacillus plantarum ATCC 8014

Abstract

The relative activity of niacin-related compounds to nicotinic acid was tested as the niacin nutriture in Lactobacillus plantarum ATCC 8014, the strain for the measurement of niacin in foods. As the results, this microorganism could use nicotinuric acid as equimolar as nicotinic acid. The relative niacin activities of N'-methylnicotinamide, pyridine 3-aldehyde, and nicotinamide N-oxide to nicotinic acid were 1/20, 1/30 and 1/40 in molar basis, respectively. While pyridine 3-methanol, nicotinic acid N-oxide, 3-acetylpyridine, β-picoline, N^1-methylnicotinamide, N^1-methylnicotinic acid, 6-hydroxynicotinic acid, 6-aminonicotinamide, quinolinic acid, and cinchomeronic acid did not show niacin activity.