Abstract
We measured the contents of B-group vitamins in the urine, serum, liver, and kidney of vitamin B_<12>-deficient rats. Urine and liver vitamin B_<12> contents in urine and liver were lower in the B_<12>-deficient rats than in the control rats. Contents of vitamin B_2, nicotinamide, and pantothenic acid in the urine, liver and kidney were not different between the B_<12>-deficient and control rats. On the other hand, contents of vitamin B_1, vitamin B_6, folate, and biotin in the urine, liver, and kidney were different between the two groups. Vitamin B_1 and folate contents in the urine, liver, and kidney were lower in the B_<12>-deficient rats than in the control rats. Vitamin B_6 content in the liver was almost equal between both groups, but, the content in urine was lower and that of kidney was higher in the B_<12>-deficinet rats than in the control rats. Biotin content in the urine and kidney was higher in the B_<12>-deficient rats, but the content in the liver was lower in the B_<12>-deficient rats.
