Synthesis and Structural Conformation of a Novel Isoxazole Derivative: 5-(3-Dimethylane-p-tolylsulfonyl)-propyl-3-(4-flurophenyl)-isoxazole

Abstract

The novel 5-(3-dimethylane-p-tolylsulfonyl)-propyl-3-(4-flurophenyl)-isoxazole was synthesized and the compound was characterized by spectroscopic techniques and finally confirmed by X-ray diffraction studies. The title compound crystallizes in the triclinic crystal class in the space group P1 with cell parameters a = 5.9350(6)Å, b = 10.1850(14)Å, c = 14.8270(2)Å, α = 104.938(4)°, β = 97.960(8)°, γ = 90.933(6)° and Z = 2. The isoxazole ring is planar. The molecular structure exhibits intermolecular hydrogen bonds of the type C-H…O. The final residual factor is R₁ = 0.0433.