Biological Effect by Altered ATP induced with Ionizing Irradiations

Abstract

Adenosine tri-phosphate (ATP), one of ribonucleic acids, acts as an intra-cellular energy transfer. ATP is also used as a substrate to synthesize messenger RNA and as a ligand of up-regulation of these biological function. In this study, we examined the relation between molecular activity, genetic information transfer, and inter-cellular signaling activity. The obtained results showed that the altered ATP molecule might contribute the induction of changing of a radiation sensitivity of cancer cells.