Abstract
A 31-year-old man was given a diagnosis of Crohn's disease at age 20, and was complicated with anorectal fistula from age 22. At age 28, seton drainage was performed because of deterioration of anorectal fistula. He underwent treatment of digestive therapy after drainage, but second surgery was performed by seton drainage because of perianal abscess. From age 29, treatmet with Infliximab was started, but he had third surgery for recurrence of anorectal fistula at age 30. His symptom was improved after seton drainage, and perianal inflammation was also improved by Infliximab. Seton drainage for anorectal fistula in Crohn's disease is efficacious both in treating inflammation and preserving anal sphincter function.