Fatal Co-infection of Crimean-Congo Hemorrhagic Fever and Malaria

I. Christova; A. Petrov; A. Papa; D. Vutchev; N. Kalvatchev; N. Vatev; M. Stoycheva

doi:10.7883/yoken.JJID.2014.106

This article has now been updated. Please use the final version.

Fatal Co-infection of Crimean-Congo Hemorrhagic Fever and Malaria

I. Christova, A. Petrov, A. Papa, D. Vutchev, N. Kalvatchev, N. Vatev, M. Stoycheva

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Keywords: CCHF, Malaria, RT-PCR

JOURNAL FREE ACCESS Advance online publication

Article ID: JJID.2014.106

DOI https://doi.org/10.7883/yoken.JJID.2014.106

The final version of this article is now available: Vol. 68 (2015), No. 2 pp. 131-134

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Abstract

Here we report a case of a Bulgarian patient with imported falciparum malaria manifested 6 days after his arrival in Bulgaria and complicated by bloody diarrhea 2 days later. Blood smear revealed high parasitaemia with annular forms and gametocytes of Plasmodium falciparum. In addition, Crimean-Congo hemorrhagic fever (CCHF) virus RNA was detected in the blood sample by real time RT-PCR and nested RT-PCR. The obtained sequence clustered within the Europe 1 lineage close to the other Bulgarian strains. It has to be noted that the two infectious diseases may appear with many similar and difficult to distinguish symptoms.

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