Japanese Journal of Infectious Diseases
Online ISSN : 1884-2836
Print ISSN : 1344-6304
ISSN-L : 1344-6304
Short Communications
Fatal Outcome of Coinfection of Crimean-Congo Hemorrhagic Fever and Malaria
Iva ChristovaAndrei PetrovAnna PapaDimitar VutchevNikolay KalvatchevNikolay VatevMariana Stoycheva
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Keywords: CCHF, malaria, RT-PCR
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2015 Volume 68 Issue 2 Pages 131-134

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Abstract

Here, we report a case of a Bulgarian patient with imported falciparum malaria that manifested 6 days after his arrival in Bulgaria, which was complicated by bloody diarrhea 2 days later. Blood smear revealed high parasitemia, with annular forms and gametocytes of Plasmodium falciparum. In addition, RNA of the Crimean-Congo hemorrhagic fever (CCHF) virus was detected in the blood sample by real-time reverse transcription (RT)-PCR and nested RT-PCR. The obtained sequence was found to be clustered within the Europe 1 lineage close to the other Bulgarian strains. Notably, the two infectious diseases may appear with many similar symptoms that are difficult to distinguish.

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