The Japanese Medical Journal
Online ISSN : 1884-281X
ISSN-L : 0368-3095
STUDY ON EQUINE ENCEPHALOMYELITIS EPIZOOTICA
KAORU OKUBOKYUZO SATOYOSHINORI ICHIKAWA
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1948 年 1 巻 2 号 p. 126-132

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In 1942 we reported on the studies of pathological anatomy of the Equine Encephalomyelitis Epizootica which had occurred in North China during the year 1940. Pathologically, it was similar to the epizootic as seen in Japan from 1935 to 1938, in which we found the intranuclear inclusion bodies, the so called “Joest-Degen's Corpuscle”, in the. nuclei of the ganglion cells and also cytoplasmic inclusion bodies, the so called “Ichii's Corpuscle”, in the protoplasma of nerve cells of Cornu Ammonis of the brain of sick horses. However, we found that contrary to the epidemic in Japan, the inflammatory changes in the cases of prolonged processes were less remarkable than in those cases which died during the acute stage. For this reason, the disease was diagnosed as “Equine Encephalomyelitis Epizootica” in North China until the causative agent could be identified as .similar to the Japanese horse encephalitis in the same manner as the Japanese B eneephalitis by virus isolation.
From the middle of July 1945, there occurred a large epizootic of horse encephalitis in wide spread districts of North China. We were able to study clinically, pathologically, anatomically, epidemiologically and virologically, several cases during the outbreak. But in as much as it was the time of surrender for Japan, we could not continue the study and were unable to carry the virus to Japan at the time of demobilization.
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