The Japanese Medical Journal
Online ISSN : 1884-281X
ISSN-L : 0368-3095
STUDIES ON THE EXTRACTION OF PENICILLIN
HAMAO UMEZAWATOMIO TAKEUCHI
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1948 年 1 巻 4 号 p. 327-338

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Principles of the extraction process of penicillin such as the solvent process and the charcoal adsorption process were found before the end of the second world war in Japan (1), but it was since November 1946, when Foster came to Japan, to undertake the systematic studies of the extraction.
At about the beginning of our study, the recovery of penicillin from the broth to the packaging in a final container in Japanese factories fluctuated between 10-40%, but now it increased to 50-80%. This increase is completely ascribable to the systematic and elaborate examinations of all the stages in the extraction process, not but to the change of the principles.
In the present paper the experiments and results concerning each stage of the extraction are described.
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