抄録
As one of the most important antibiotics, streptomycin has been studied in detail by many workers after the discovery of Waksman and his colleagues (1), but it has been a very difficult work to isolate a streptomycin-producing strain, until recently the above author (2) found a rapid isolation method. Thereafter several active strains were isolated also by us (3) and afterwards two strains by other Japanese workers in obedience to our publication (3) . The fact that all active strains obtained both in America and in Japan belong to S. griseus seems to suggest the existence of a specific relation betweenn streptomycin and S. griseus. But hitherto an antibiotic substance has been usually obtained from more than. one species, such as penicillin from P. chrysogenum notatum, A. flavus and etc, Patulin from P. patulum, P. expansum, P. leucopus, P. claviforme and A. clavatus, While we were classifing numerous antibiotic strains of strepomyces according to their antibacterial spectra, we found several strains producing a pink pigment and possessing the streptomycin-producing ability. Waksman and others (4) recently observed Streptomyces bikiniensis to produce a streptømycin-like substance, however these strains seem to be different from this strain. The antibiotic obtained from our strains conforms to streptomycin in its antibácterial spectrum, toxicity, solubility in various solvents and colour of Sakaguchi's reaction.
Present paper describes the isolation of the strains, and various foundations to decide it to be streptomycin. The characters of the strain in detail will be published elsewhere.
