Abstract
Streptomycin was discovered by Waksman, Schatz and Bugie of the New Jersey Agricultural Experiment Station, Rutgers University, during the course of a systematic program devoted to the study of antibiotic materials, begun in 1939, and the antibacterial properties of this new antibiotic agent have since been well established by the works of many investigators. Indeed, as the results of such works, streptomycinn has, in addition to exhibiting marked antibacterial effect against gram-negative organisms, also shown possibilities as a chemotherapeutic agent against infections duo to Mycobacterium tuberculosis.
Another antibacterial agent characterized by tuberculo-bacteriostatic properties. T is o-aminophenol, a synthetic product, reported by Okamoto and his co-workers in 1924.
Recently, the writers have had an opportunity to carry out some comparative experiments with streptomycin and o-aminophenol. The results of these experiments are reported here.
