Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
A RECENT CASE OF BOTULISM IN HOKKAIDO, JAPAN
JAMES M. CRAIG飯田 広夫井上 勝弘
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1970 年 23 巻 3 号 p. 193-198

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A case of type E botulism due to “izushi” made of “hata-hata” and flatfish occurred in Asahikawa, Hokkaio, in January, 1970. The remains of the “izushi” left after the fatal consumption was not available for testing, but the fecal sample tested was found to contain a toxin level of 6750 mouse LD50 per g of feces. The toxin in the fecal sample was identifed as type E botulinal toxin by antitoxin neutralization tests using mice. Isolation of Cl. botulinum type E was achieved by alcohol treatment and serial dilution with the use of lecithinase production to assist in recognition.
The patient continued to sink and expired 109 hr after ingestion of the “izushi”.
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