抄録
The asymmetric ring opening of meso-epoxides with variety of nucleophiles is an important transformation to produce 1,2-bifunctionalized systems and to establish two contiguous stereogenic centers in a single event. This mini-review focuses on the recent advances in asymmetric ring opening of meso-epoxides with halogen-containing nucleophiles to afford the vicinal halohydrins. The vicinal halohydrins can be utilized for some useful synthetic transformations, and are also key imtermediates in the synthesis of natural products.
