Search for Bioactive Natural Products Targeting Cancer–Related Signaling Pathways

Abstract

During our studies related to the search for bioactive natural products, we recently examined extracts of various natural resources including unexplored myxomycetes, marine organisms, as well as several medicinal plants collected in the north–eastern part of Thailand and Bangladesh. Here we describe our recent results from our screening programs targeting signaling molecules in cancer–related biological pathways such as TRAIL, Wnt, and Hedgehog signalings.