Abstract
An extracelluler matrix is collapsed and a cell is revealed by hyaluronidase resolving hyaluronic acid. As this result, a pathogen, an inflammation mediation material, and various kinds of medicines such as an inflammation agent or a preservative will damage the revealed cell. Therefore it is expected that hyaluronidase inhibitor causes antiinflammation and anagenesis. It is known that a lot of sulfated polysaccharides have hyaluronidase inhibition activity. We focused cellulose sodium sulfate, which is a kind of sulfated polysaccharides, and evaluated the hyaluronidase inhibition activity of cellulose sodium sulfate. Then, we investigated the close relation with a skin and cellulose sodium sulfate. We confirmed that cellulose sodium sulfate has superior hyaluronidase inhibition ability, and is a promising material having the superior moisture retention characteristics.
