Palladium-Catalyzed 1,1-Difunctionalization of Terminal Alkenes

Abstract

Palladium-catalyzed difunctionalization of alkenes, which forms two new σ-bonds in a single step, is attractive for synthesizing complex molecules. This short review summarizes 1,1-difunctionalization reactions of terminal alkenes, which have been emerging as a new tool that complements the conventional 1,2-difunctionalization.