Journal of Synthetic Organic Chemistry, Japan
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
Review de Debut
Biomimetic Transamination of α-Keto Esters
Takumi Abe
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JOURNAL OPEN ACCESS

2013 Volume 71 Issue 1 Pages 62-63

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Abstract
The development of biomimetic reactions is one of the major challenges for synthetic chemists, because mimicking these complicated reactions in the laboratory by simple catalytic systems is difficult to achieve in general. Vitamine B6-dependent aminotransferase-catalyzed transamination of α-keto acids from pyridoxamine is an important process to generate α-amino acids in nature. In this review, recent progresses on the biomimetic transamination of α-keto esters are described.
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© 2013 The Society of Synthetic Organic Chemistry, Japan
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