Abstract
Organicboronic acids are commonly used in organic synthesis, although unstable boronic acids are known to decompose competitively in the cross coupling reaction. Recently Burke developed a novel organoboron strategy that allows for the control of cross coupling reaction by using N-methyliminodiacetic acid (MIDA) as boron-protecting group. In this review, the application of MIDA boronate for total syntheses of natural product and the novel development of sp3 hybridized boronate chemistry are described.
