Abstract
NMR (Nuclear Magnetic Resonance) is a useful tool to analyze products of chemical synthesis. However, when by-products are synthesized simultaneously, analyses by NMR become a challenge due to spectral overlapping of each component. For analyses of such mixtures by NMR, very useful method DOSY (Diffusion Ordered SpectroscopY) was proposed in 1990’s. It enables to separate spectra of mixtures into each component by using the difference of individual self diffusion coefficients. In this article, I introduce DOSY from its principle to practical experiments, and show an example of application for analysis of reaction pathway.
