2014 Volume 72 Issue 9 Pages 972-982
Though the synthetic reactions of C-C multiple bonds directly having functional groups are more effective to give functionalized compounds which are easily converted to useful compounds like natural products and drugs, the applicability of this process to functionalized C-C multiple bonds is limited, probably because of the poor compatibility of the reactive metallic portion and the functional group. We focused on the interaction between transition metals and functionalized C-C multiple bonds, and have developed new synthetic methods using the above interaction and its synthetic applications. We discussed the new synthetic methods disclosed by as will be described using iron reagents in detail in this paper.