2016 年 74 巻 1 号 p. 71-72
Recently, the direct functionalization of unactivated C(sp3)-H bonds have been well developed. Despite their numerous efforts, controlling the site-selectivity in these transformations is still challenging because a multitude of C-H bonds has close dissociation energies. In this mini-review, successful examples to control site-selectivity in C(sp3)-activation reaction by changing reagents or catalysts is described.