Catalytic Markovnikov Hydroboration of Unactivated Terminal Alkenes

Abstract

Regio- and stereoselective synthesis of organoboron compounds has great importance due to their wide applicability and high stereospecificity in many transformations such as Suzuki-Miyaura cross coupling reaction. Generally, hydroboration of unactivated terminal alkenes proceeds in anti-Markovnikov selective manner to produce linear products. In this short review, recent examples of catalytic Markovnikov hydroboration of unactivated terminal alkenes, and its application to asymmetric synthesis are described.