有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
Review de Debut
Neooxazolomycinの不斉全合成
藤原 広一
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ジャーナル オープンアクセス

2020 年 78 巻 6 号 p. 634-636

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Neooxazolomycin is an antitumor agent isolated by Uemura in 1985. Due to the complexity of highly functionalized lactam-lacton core and the instability of polyene moiety to acid, base, and light, there are only few reports on its total synthesis. In this short review, the total syntheses of neooxazolomycin reported by three groups are described focusing on the construction of lactam-lactone skeleton.

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