Site-selective Functionalization of Arenes by “Sulfonium Salt Formation/Coupling Reaction”

Abstract

Site-selective functionalization of arenes is a long-standing issue in organic synthesis. Sulfonium salt formation of arenes by a S_EAr reaction is one of the solutions of this challenge. These salts are ready to engage in various transformations such as cross-coupling reactions. This review summarizes the site-selective functionalizations of aromatic compounds by “sulfonium salt formation/coupling reaction”.