2021 年 79 巻 9 号 p. 819-828
In the field of plant science, strigolactones (SLs) are one of the groups of compounds that have received the most attention in recent years. The first SL, strigol, was introduced to the world of natural product chemistry in 1966. For the next 40 years, SLs have been recognized as seed germination stimulants for root parasitic weeds. However, this situation has changed drastically in the past 15 years, as SLs were reported to be signaling substances in arbuscular mycorrhizal symbiosis in 2005 and a new class of plant hormones regulating shoot branching in 2008. Since then, attention to SL has increased dramatically, and SL-related research has been progressing rapidly. However, while there are many review articles written from the perspective of plant science, there are very few written from the perspective of synthetic organic chemistry. Therefore, in this paper, I would like to review the history of SL research and introduce SL research from the viewpoint of synthetic organic chemistry, focusing on my own research. In addition to the synthetic studies on natural SLs, the application of artificial SL analogs for the control of root parasitic weeds and attempts to help elucidate the biosynthetic pathway of SLs are also presented.