歪んだ低分子アルカロイドHerquline類の全合成

抄録

Herqulines are small alkaloids with highly distorted structures that are synthesized from two tyrosine molecules. Between December 2018 and January 2019, the excellent total syntheses of herqulines B and C were reported by the groups of Wood, Baran, and Schindler. In 2022, the group of Han reported the synthesis of 1-hydroxyherquline A; however, the total synthesis of herquline A has not yet been achieved. In this short review, we will give an overview of the studies reported to date that focused on the syntheses of the herquline family.