Abstract
Reductive aminolysis of ethanolamine, isopropanolamine, and 2-methyl-2-aminopropanol in the presence or absence of ammonia was investigated. Good yield of corresponding piperazine derivatives was obtained in the presence of ammonia. The yield of products was different depending on the kinds of amino alcohols used and it was in order of 2-methyl-2-amino-propanol>isopropanolamine>ethanolamine. The main product of reaction in the absence of ammonia seemed to be diamino alcohol, although the experimental results indicated that the formation of N, N'-diethylpiperazine from ethanolamine, and triisopropylenediamine from isopropanolamine was confirmed. The main product was also piperazine derivatives from 2-amino-2-methyl-propanol. This was attributed to an obstruction of diamino alcohol formation from its structure. Similar experi ment was carried out on propylenediamine to recover only unreacted raw material.
