3-ニトロフタル酸の接触還元反応

抄録

It was found that 3-nitrophthalic acid (1) was reduced to 3-aminophthalic acid (2) in the presence of 5% palladium-charcoal in glacial acetic acid under the atmospheric pressure at room temperature. 3-Acetylaminophthalic anhydrde (3) was synthesized in 90% yield (based on 1) by heating (2) in a mixture of acetic anhydride and glacial acetic acid. (3) was hydrolyzed to 3-acetylaminophthalic acid, mp 210211°C (dec.), in hot water.