Abstract
1, 3-Dipolar cycloaddition of N- (p-substituted benzylidene) -p-substituted benzylamine N-oxides with trans-1, 2-bis (p-substituted benzoyl) ethylenes was carried out to give trans-and cis-2, 3-bis (p-substituted phenyl) -4, 5-bis (p-substited benzoyl) isoxazolidines. The configurations of the resulting isoxazolidines were determined by NMR spectra. The formation ratios of trans-to cis-adducts were determined by liquid chromatography. Kinetic parameters, the activation energy, the activation enthalpy and the activation entropy were determined. The solvent effects were discussed from the view point of the reaction rates or the formation ratios.
