典型金属の特性を活かした有機合成

抄録

The concept of combined acid-base attack is important for understanding the behaviour of R₃Al or R₂AlX type reagents as well as to explore further synthetic applications. The topics will involve such molecular rearrangements as Clisen type, pinacol-pinacolone type, and alk-5-en-5-olides-cyclohexane-1, 3-diones type. All rearrangements are induced by the action of organoaluminium reagents and the former two proceed under uptake of nucleophiles from aluminium on the carbonyl carbon. Reaction of enol phosphates with organoaluminium reagents is catalyzed by Pd (PPh₃) ₄ complex to produce C=C-R type products.