ペネム化合物の合成と抗菌活性
1983 年 41 巻 12 号 p. 1168-1180
詳細
1983 年 41 巻 12 号 p. 1168-1180
This article is intended to give a brief review of synthetic methods of penems, ranging from Woodward's first penem synthesis to the most recent penem synthesis appearing in current papers. The antibacterial in vitro activities of a variety of penem derivatives are also described, together with structure-activity relationships of penems prepared in our laboratories.
