有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
プロスタグランディンの開発動向
平田 文雄
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ジャーナル フリー

1983 年 41 巻 2 号 p. 178-185

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The current status of prostaglandin research is reviewed mainly on the primary prostaglandins, widely distributed in the living body, and on prostaglandin analogues having more stable structure and higher selective biological activities, which were developed by reference to the structures and activities of the primary PGs. Especially, recent aspect on their clinical application and development is explained. Moreover, the new field is viewed mainly on the future commercialization of PGI2 and TXA2 synthesis inhibitor, which will be applied mainly on circulatory system, from Yin-Yang theory. Further, recent rapid progress in leukotriene research on lipoxygenase system in arachidonic acid cascade will also been mentioned.
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