Abstract
Arachidonic acid is converted into biologically important substances, one of the most conspicuous being thromboxane A2 because of its outsanding potent platelet aggregating and smooth muscle contracting activities. Since thromboxane A2 is extremely labile, the synthesis of natural thromboxane A2 has not been reported yet. This review focuses the synthesis of thromboxane A2 analogs having the agonistic and antagonistic activities.
