Regioselective Syntheses of Acylated Mono-saccharides and Their Acyl Migration

Regioselective Modifications of a Hydroxyl Group in Carbohydrates

Abstract

This article critically reviews the reactivity of hydroxyl groups in mono-saccharides toward direct acylation and describes the method of regioselective modifications (acylation, alkylation, etc) of a hydroxyl group without blocking-deblocking technique via cyclic tin intermediates. O-Acyl migration in mono-O-acyl derivatives of D-glucose and L-arabinose under various conditions is also discussed.