Journal of Synthetic Organic Chemistry, Japan
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
X-ray Crystal Structure Analyses of Biological Macromolecules
Recent Advances
Takamasa NONAKAYukio MITSUI
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1993 Volume 51 Issue 6 Pages 551-562

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Abstract
During the last decade, we have witnessed significant advances in various technological aspects of a discipline called “protein crystallography” which is a branch of the technique of X-ray crystal structure analyses specifically aimed at solving the crystal structures (and thus the molecular structures) of biological macromolecules. After the introductory sections dealing with 1) the relationship of the present field with organic chemistry and 2) the rationale for further promotion of the technique of protein crystallography, the advances in various technological aspects are summarized in the form of Table 1. Finally more detaild accounts are given for 1) the method and prospect of time-resolved X-ray crystal structure analysis using the Laue method and 2) the present situation of the Brookhaven Protein Data Bank.
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© The Society of Syhthetic Organic Chemistry, Japan
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