有機化合物の不斉結晶化

不斉の場無しでの不斉の出現 (その1)

抄録

Chiral crystallization of optically inactive (achiral) compounds such as benzophenone, phenol, phenanthrene, etc. has not been a commonly known phenomenon in organic chemistry. These compounds are known to crystallize to chiral crystals from their solutions. This review deals with this phenomenon, describing (1) what is chiral crystallization and how to find organic compounds undergoing chiral crystallization, (2) the preparation of chiral crystals from achiral organic compounds, (3) the characterization of chiral crystals, (4) the crystal structure of chiral crystals and the factors of the generation of chirality, (5) the chiral crystallization of two-component molecular compounds, (6) absolute asymmetric synthesis utilizing chiral crystallization, (7) other applications of chiral crystallization. Part 1 describes chapters (1), (2), (3), and (4).