Preparative Routes to Organozinc Reagents Used for Organic Synthesis

Abstract

Organozinc reagents have become extremely important synthetic tools in recent years, and the useful and practical preparative routes to such reagents have been reviewed. The methods have been classified into four broad categories, (1) oxidative zincation method, (2) transmetalation method, (3) halogenzinc exchange, and (4) others. Each categories are subdivided according to the type of organic groups on the zinc atom (alkyl, alkenyl, etc.).