不均一系立体区別触媒

不斉修飾ニッケル (MNi) の立体化学をもとにした研究の展開

抄録

Almost perfect enantio-differentiating hydrogenation was achieved by heterogeneous catalyst. Tartaric acid-NaBr modified supersonicated Raney nickel (TA-NaBr-MRNiU) showed 98.6% of e.d.a. in the hydrogenation of methyl 3-cyclopropyl-3-oxopropanoate. Three emprical modeles; “catalyst region model”, “reaction process model”, and “stereochemical model”, proposed for the explanation of the functions of MNi enable us to design the present reaction system. The development of the models and their contribution for the improvement of the catalyst and its reaction system are described.