Journal of Synthetic Organic Chemistry, Japan
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
Synthetic Studies of Fluorine-containing Compounds for Household Insecticides
Tatsuya MoriNoritada Matsuo
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2007 Volume 65 Issue 6 Pages 620-625

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Abstract
It is well recognized that the ratio of fluorine-containing pesticides is increasing along with the progress of fluorine chemistry. In recent years, one third of new pesticides are containing fluorine atom (s). In many cases, they have remarkable pesticidal activity as well as physicochemical properties by introduction of fluorine atom (s). We describe the discovery stories of three examples in our laboratory, i.e. amidoflumet, a new trifluoromethanesulfonanilide with high miticidal activity against various house dust mites, Metofluthrin, a potent new fluorinated pyrethroid with extremely high knockdown activity against various mosquitoes, and a new α-pyrone compound, 3- [1R-trans- (2-trifluoromethyl) cyclopropane carbonyl] -4-hydroxy-6-methyl-2-pyrone with outstanding insecticidal activity against Blattella germanica.
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© The Society of Syhthetic Organic Chemistry, Japan
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