Abstract
This short review describes the recent development on β-mannosidic bond formation. Though the formation of β-mannoside is rather difficult in chemical synthesis, following two useful representative methods are reported; 1) introducing an acetal moiety as an acceptor on a donor as the stereocontroling element for intramolecular β-mannosylation; 2) using a donor having cyclic acetal protecting group at O-4, 6 position. As for the later, it was reported that the introduction of propagyl group at O-2 position improved β-selectivity even if a donor having steric protecting group at O-3 position was employed. Catalytic and β-selective mannosylation is also noted.
