有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
高度に歪んだパラシクロファン骨格を有する八オウアミン類の合成研究
岡野 健太郎
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ジャーナル フリー

66 巻 (2008) 4 号 p. 387-388

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Recent development of synthetic studies on novel marine alkaloids, haouamine A and B, is described. Haouamines have attracted considerable attention of synthetic chemists because of their unique structure and selective activity against human colon carcinoma cell line HT-29, however, only two groups have so far reported successful formation of their highly strained 3-aza-[7]-paracyclophane core. This review focuses on synthetic efforts to construct the core skeleton of haouamines reported by Baran and Wipf.

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