NBCA has been reported as an effective embolic agent but there are some drawbacks to control the embolic range. Some techniques such as “Wedge injection” have been advocated to overcome these drawbacks but the optimal techniques have been not confirmed. Therefore, the safety and effectiveness of embolization depend on the operator’s ability and experience.
We advocated the new NBCA injection technique named “B-glue” which is the NBCA injection during a vascular occlusion with a recently developed microballoon catheter.
The purpose of this review is to describe the methods, characteristics, limitations and future of B-glue, based on the reported animal experiments and case reports. Further evaluation such as optimal NBCA-lipiodol dilution ratio and waiting time between NBCA injection and balloon deflation is necessary. It has been also uncertain whether B-glue can be applied for larger vessels or complex vascular network. Moreover, uncertainty of a potential risk of stronger adhesion to the vascular wall remains because balloon structures have a larger surface.
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