The attempt to monitor the socio-economy as a system configuration is nothing but an analysis from a scientific perspective (i.e., from a third party's viewpoint). Even if the selection decisions for system selling related to innovation and sustainability are oriented toward total optimization, it is impossible to avoid vulnerability caused by discrepancies in consensus building at the initial start-up stage of "Koto" (three different Japanese of "Koto"). Moreover, even if selection decisions similar to those of a resilience-oriented ecosystem are used, consensus building to trace the network of "Mono" (three different Japanese of "Mono") does not guarantee the overall optimization of the system. The idea of Global supply-chain is not new. However, it will require methodological restructuring to seek consensus building not only at each step of multi-stages but also onto a collective level.

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This paper takes nanotechnology as an example for precautionary measures against risks associated with the scientific uncertainty of advanced science and technology and based on the scientific uncertainty, divides the subject of regulation into the elements of "technology" and "materials". Then, taking into consideration the "function" and "property" of science and technology, the social acceptability and validity are relatively guaranteed when the subject of regulation is divided by using precautionary measures compared to the case where it is not divided. This finding may lead to an approach that further reduces the occurrence of social inconvenience. In addition, compared to foreign countries such as the EU, which have already established regulatory measures regarding nanotechnology, Japan has not taken any concrete precautionary measures. Under such circumstances, this paper presents a new perspective including policy suggestions on the outlook for future nanotechnology regulation in Japan.

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